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Oct 26, 2018 · Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53 Skip to main content Thank you for visiting nature.com.

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Nov 07, 2019 · CBP/p300 proteins are key coactivators of AR and enhance the response to androgens. CBP/p300 proteins have an oncogenic role in PCa in a cellular context‐dependent manner (Ding et al, 2014; Zhong et al, 2014), consistent with the finding that p300 is often deregulated in PCa patient samples (Debes et al, 2003).

Author: Yuqian Yan, Jian Ma, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi,

Detecting P300 signals from electroencephalography (EEG) is the key to establishing a P300 speller, which is a type of braincomputer interface (BCI) system based on the oddball paradigm that allows users to type messages simply by controlling eye-gazes.

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CBP/p300 proteins are key coactivators of AR and enhance the response to androgens. CBP/p300 proteins have an oncogenic role in PCa in a cellular context‐dependent manner (Ding et al, 2014; Zhong et al, 2014), consistent with the finding that p300 is often deregulated in

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Oct 26, 2018 · Interestingly, p300-mediated acetylation of H3 at Lys56 was reported to inhibit cell proliferation, colony formation and migration of cancer cell lines, including hepatoma, through regulation of

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Both P300 potential and SSVEP can be elicited by visual stimuli, allowing subjects to evoke both brain patterns by performing a visual attention task without extra mental load. The P300 and SSVEP features are located in different domains (time domain versus frequency domain), and both brain patterns have significant independence.

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In vivo hypoxia experiments were performed as previously described 43 using an oxygen control cabinet system (Guizhou Aviation Industry Co. Ltd., Guizhou, China; Model: FLYDWC50‐IB) (Supplemental Fig. S7). Briefly, mice were subjected to systemic normobaric hypoxia by substituting oxygen with nitrogen at a constant gas flow rate in the closed

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Nov 11, 2019 · Due to lack of DNA‐binding domain, EWSR1 usually acts as a potent transcriptional cofactor in tumor progression via interacting with transcription regulatory proteins, such as CREB‐binding protein and p300 (Chakravarti et al, 1996). In this study, we found that RRM domain of EWSR1 was necessary for its interaction with ZNF domain of MAZ.

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However, NEO2734, a novel dual inhibitor of BET and CBP/p300, is active in both hotspot mutant (F133V) and non-hotspot mutant (Q165P) PCa cells in vitro and in vivo.

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